6/27/2023 0 Comments The first Chapter by Kerry GirlingSpecial attention should be paid to the potential for bias arising from carry-over of effects from one period to the subsequent period of the trial, and to the possibility of ‘period effects’. Special attention should be paid to the potential for bias arising from how individual participants were identified and recruited within clusters.Ī variant of the risk-of-bias assessment tool is available for crossover trials. If the authors of studies included in the review fail to account for correlations among outcome data that arise because of the design, approximate methods can often be applied by review authors.Ī variant of the risk-of-bias assessment tool is available for cluster-randomized trials. Non-standard designs, such as cluster-randomized trials and crossover trials, should be analysed using methods appropriate to the design.
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